Several hereditary disease loci have been genetically mapped to the chromosome 1q24-q31 interval, including the hereditaryprostatecancer 1 (HPC1) locus.
Ús de familial prostate cancer en anglès
1
Interestingly, the G allele of rs6983267 was associated with familialprostatecancer risk.
2
It is also possible that CYP17 interacts with other genes that influence risk of familialprostatecancer.